Englumafusp alfa is a CD19/4-1BB antibody construct designed to enhance immune response by promoting CD19-specific cross-linking of the 4-1BB receptor on T and NK cells. This fusion protein consists of a CD19-specific antibody domain linked to trimerized extracellular domains of human 4-1BB ligand (41BBL). Its key biological activity supports investigations into immuno-oncology applications, particularly in targeting CD19-positive malignancies. Researchers can utilize Englumafusp alfa to study T cell activation and proliferation in the context of cancer therapies.
Englumafusp alfa is a CD19/4-1BB antibody construct designed to enhance immune response by promoting CD19-specific cross-linking of the 4-1BB receptor on T and NK cells. This fusion protein consists of a CD19-specific antibody domain linked to trimerized extracellular domains of human 4-1BB ligand (41BBL). Its key biological activity supports investigations into immuno-oncology applications, particularly in targeting CD19-positive malignancies. Researchers can utilize Englumafusp alfa to study T cell activation and proliferation in the context of cancer therapies.
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