Fig. 1 · Structure

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Enofelast

Cat. No. A61013 CAS 125722-16-9

5-LO Inhibitor

Enofelast (BI-L-239) is a selective inhibitor of 5-lipoxygenase (5-LO) with an IC50 of 2.48 μM, effectively blocking calcium ionophore-induced leukotriene B4 (LTB4) production. Its ability to modulate lipid mediators makes it a valuable tool for studying inflammatory pathways and leukotriene signaling in various biological contexts. Enofelast is suitable for research applications investigating the role of 5-LO in diseases associated with inflammation and immune response.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 125722-16-9
Applications 5-LO Inhibitor
Formula C16H15FO
Molecular Weight 242.29
Synonyms BI-L-239
SMILES
OC1=C(C=C(C=C1C)/C=C/C2=CC=C(C=C2)F)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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