Fig. 1 · Structure

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ent-Avibactam sodium

Cat. No. A50429 CAS 396731-20-7

Beta-lactamase Inhibitor

Ent-Avibactam sodium is a β-lactamase inhibitor designed to combat a wide range of bacterial infections. It effectively inhibits Ambler A and C type β-lactamases produced by Enterobacteriaceae, enhancing the efficacy of β-lactam antibiotics like Cefazidime. With an IC50 value significantly lower than other commonly used β-lactamase inhibitors, ent-Avibactam sodium demonstrates superior potency against TEM-1 and P99 enzymes, making it a valuable tool for bacterial resistance research and antibiotic development.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 396731-20-7
Applications Beta-lactamase Inhibitor
Formula C7H10N3NaO6S
Molecular Weight 287.23
Synonyms AVE1330A
SMILES
NC([C@@H]1[N@]2C(N([C@@H](CC1)C2)OS(=O)(O[Na])=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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