Fig. 1 · Structure
Documents & Downloads
Enzastaurin hydrochloride
PKCβ Inhibitor
Enzastaurin hydrochloride is a potent and selective inhibitor of protein kinase C beta (PKCβ), exhibiting an IC50 of 6 nM. This compound demonstrates a 6- to 20-fold preference for PKCβ over other isoforms, including PKCα, PKCγ, and PKCε. Enzastaurin is utilized in research focused on cancer therapeutics and signal transduction pathways, providing insights into the role of PKCβ in cellular processes and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 359017-79-1 |
| Applications | PKCβ Inhibitor |
| Formula | C32H30ClN5O2 |
| Molecular Weight | 552.07 |
| Synonyms | LY317615 hydrochloride |
| SMILES | O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3C4=CN(C5CCN(CC6=NC=CC=C6)CC5)C7=C4C=CC=C7)NC3=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.