Enzyme-IN-1

Catalog No.: A77329
Proteasome Inhibitor
Enzyme-IN-1 is a potent proteasome inhibitor that targets the chymotrypsin-like activity (CT-L) of the 20S proteasome, specifically inhibiting N-terminal nucleophile (Ntn) hydrolases. This compound has demonstrated key biological activity in modulating protein degradation pathways, which may confer potential anti-inflammatory properties. Enzyme-IN-1 is suitable for research applications focused on studying proteasome-related processes and their implications in various disease models.
Grouped product items
Size Price Stock Qty
1mg
$160.00
In stock
5mg
$360.00
In stock
10mg
$555.00
In stock
25mg
$1,110.00
In stock
50mg
$1,730.00
In stock
100mg
$2,705.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEnzyme-IN-1 is a potent proteasome inhibitor that targets the chymotrypsin-like activity (CT-L) of the 20S proteasome, specifically inhibiting N-terminal nucleophile (Ntn) hydrolases. This compound has demonstrated key biological activity in modulating protein degradation pathways, which may confer potential anti-inflammatory properties. Enzyme-IN-1 is suitable for research applications focused on studying proteasome-related processes and their implications in various disease models.
Product Information
Catalog NumA77329
FormulaC36H50N4O7
Molecular Weight650.80
CAS Number868540-02-7
SMILESOCC(N[C@@H](CCC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C([C@]3(CO3)C)=O)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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