Fig. 1 · Structure
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EP2 receptor antagonist-2
EP2 Receptor Antagonist
EP2 receptor antagonist-2 (CID891729) is a selective antagonist of the EP2 receptor, effectively inhibiting PGE2-induced receptor activation. This compound also demonstrates the ability to suppress lactate dehydrogenase (LDH) release triggered by N-methyl-D-aspartate (NMDA). It is valuable for research applications focused on inflammatory responses and neuronal excitotoxicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 615273-95-5 |
| Applications | EP2 Receptor Antagonist |
| Formula | C15H14F3N3O |
| Molecular Weight | 309.29 |
| SMILES | FC(F)(C1=CC(C2=CC=CC=C2)=NC(N3CCOCC3)=N1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.