EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, exhibiting an IC50 of 8 nM in human EP2 SPA assays and 50 nM in human EP2 cAMP assays. It enhances macrophage-mediated clearance of Amyloid-β plaques, making it a valuable tool for research into Alzheimer's disease and related neurodegenerative disorders. This compound can aid in understanding the role of EP2 receptors in immune response and amyloid pathology.
EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, exhibiting an IC50 of 8 nM in human EP2 SPA assays and 50 nM in human EP2 cAMP assays. It enhances macrophage-mediated clearance of Amyloid-β plaques, making it a valuable tool for research into Alzheimer's disease and related neurodegenerative disorders. This compound can aid in understanding the role of EP2 receptors in immune response and amyloid pathology.
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