Fig. 1 · Structure
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EP3 antagonist 2
EP3 Receptor Antagonist
EP3 antagonist 2 is a potent and selective antagonist of the EP3 receptor, exhibiting a strong binding affinity with a Ki value of 3.3 nM. This compound demonstrates significant antagonistic activity, with an IC50 of 30.8 nM, as determined by its ability to modulate cellular cAMP levels. EP3 antagonist 2 is suitable for research applications exploring the physiological roles of the EP3 receptor in various biological processes and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1952261-87-8 |
| Applications | EP3 Receptor Antagonist |
| Formula | C21H21N3O2 |
| Molecular Weight | 347.41 |
| SMILES | O=C1C([C@]2(C)C(NCCC2)=O)=CC=C(C3=CC4=C(C)C=CC=C4N=C3)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.