EP3 antagonist 2 is a potent and selective antagonist of the EP3 receptor, exhibiting a strong binding affinity with a Ki value of 3.3 nM. This compound demonstrates significant antagonistic activity, with an IC50 of 30.8 nM, as determined by its ability to modulate cellular cAMP levels. EP3 antagonist 2 is suitable for research applications exploring the physiological roles of the EP3 receptor in various biological processes and potential therapeutic interventions.
EP3 antagonist 2 is a potent and selective antagonist of the EP3 receptor, exhibiting a strong binding affinity with a Ki value of 3.3 nM. This compound demonstrates significant antagonistic activity, with an IC50 of 30.8 nM, as determined by its ability to modulate cellular cAMP levels. EP3 antagonist 2 is suitable for research applications exploring the physiological roles of the EP3 receptor in various biological processes and potential therapeutic interventions.
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