Fig. 1 · Structure
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EP3 antagonist 3
EP3 Antagonist
EP3 antagonist 3 is a potent and selective antagonist of the EP3 receptor, exhibiting a pKi value of 8.3. This compound demonstrates excellent pharmacokinetic properties, making it suitable for in vivo studies. EP3 antagonist 3 is primarily utilized in research related to overactive bladder (OAB), providing valuable insights into potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1227827-88-4 |
| Applications | EP3 Antagonist |
| Formula | C21H18N2O4 |
| Molecular Weight | 362.38 |
| SMILES | O=C1OC(C2=CC=C(C3=CC4=C(C=CC=C4)C=C3)NC2=O)(C(C)C)C(N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.