EP3 Antagonist 4 is a selective antagonist of the EP3 receptor, exhibiting a Ki value of 2 nM for human EP3. It demonstrates low in vivo clearance and high oral bioavailability, as evidenced by pharmacokinetic studies in rats. This compound is primarily utilized in the research of beta cell dysfunction in diabetes, contributing to our understanding of metabolic disorders and potential therapeutic interventions.
EP3 Antagonist 4 is a selective antagonist of the EP3 receptor, exhibiting a Ki value of 2 nM for human EP3. It demonstrates low in vivo clearance and high oral bioavailability, as evidenced by pharmacokinetic studies in rats. This compound is primarily utilized in the research of beta cell dysfunction in diabetes, contributing to our understanding of metabolic disorders and potential therapeutic interventions.
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