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EP3 antagonist 6

EP3 Receptor Antagonist

EP3 antagonist 6 is a selective EP3 receptor antagonist that demonstrates a potent inhibitory effect with an IC50 of 1.9 nM. This compound effectively blocks PGE2-induced uterine contractions in pregnant rat models, making it a valuable tool for exploring reproductive physiology and therapeutic interventions in uterine contractility. Its application in research can help elucidate the role of EP3 receptors in various biological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	499149-94-9
Applications	EP3 Receptor Antagonist
Formula	C₃₁H₃₇NO₄
Molecular Weight	487.63
SMILES	CC(C)C[C@H](C1=CC(C)=CC(C)=C1)NC(C2=C(C=CC(COC3=C(C=CC=C3)C)=C2)CCC(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.