Epiboxidine hydrochloride is a potent and selective agonist of the nicotinic acetylcholine receptors (nAChRs), exhibiting Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. This compound, a methylisoxazole analog of the alkaloid Epibatidine, plays a critical role in studying nAChR-mediated signaling pathways. Its high affinity and selectivity make it valuable for research applications in neurobiology and pharmacology, particularly in the exploration of neurological disorders and drug development targeting nAChRs.
Epiboxidine hydrochloride is a potent and selective agonist of the nicotinic acetylcholine receptors (nAChRs), exhibiting Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. This compound, a methylisoxazole analog of the alkaloid Epibatidine, plays a critical role in studying nAChR-mediated signaling pathways. Its high affinity and selectivity make it valuable for research applications in neurobiology and pharmacology, particularly in the exploration of neurological disorders and drug development targeting nAChRs.
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