Epiboxidine is a potent and selective agonist of neural nicotinic acetylcholine receptors (nAChRs), demonstrating Ki values of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. As a methylisoxazole derivative of the alkaloid Epibatidine, Epiboxidine serves as a valuable tool for studying nAChR-related pathways and their physiological functions. This compound is instrumental in exploring the potential therapeutic applications in neuropharmacology and other related fields.
Epiboxidine is a potent and selective agonist of neural nicotinic acetylcholine receptors (nAChRs), demonstrating Ki values of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. As a methylisoxazole derivative of the alkaloid Epibatidine, Epiboxidine serves as a valuable tool for studying nAChR-related pathways and their physiological functions. This compound is instrumental in exploring the potential therapeutic applications in neuropharmacology and other related fields.
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