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YTHDF

YT521-B homology domain family (YTHDF) proteins participate in recognition of methylated ribonucleic acid (RNA). The family is studied as part of post-transcriptional regulation, linking chemical marks on transcripts to their cellular handling. YTH-IN-1 is listed as an inhibitor across several YTH domain proteins, while YTHDF2 ligand-1 is assigned as a ligand of family member 2. The selection also contains compounds with broader biological annotations. These differences matter when distinguishing direct reader-protein ligands from compounds associated with related pathways.

2 Items

  • YTH-IN-1
    Cat. No.
    A40285
    CAS No.
    2189366-92-3

    YTH-IN-1

    YTH-IN-1 is a pan-YTH domain inhibitor that targets various YTH domain-containing proteins. It exhibits IC50 values of 39 μM, 34 μM, 35 μM, 48 μM, and 30 μM for human YTHDF1, YTHDF2, YTHDF3, YTHDC1, and YTHDC2 respectively. This compound is utilized in research to explore the role of YTH domain proteins in RNA metabolism and epitranscriptomics, making it a valuable tool for studying gene regulation and cellular responses.

    In stock View Details
    1 mg
    $195.00
    5 mg
    $485.00
    All 6 sizes
  • YTHDF2 ligand-1
    Cat. No.
    A57868
    CAS No.
    3093182-34-1

    YTHDF2 ligand-1

    YTHDF2 ligand-1 is a selective and high-affinity ligand that targets YTHDF2, with an IC50 of 11 μM and a Kd of 1.3 μM. This compound effectively competes with m6A-RNA for the binding site on YTHDF2, making it a valuable tool for studies involving RNA methylation and its implications in cancer research. Researchers can utilize YTHDF2 ligand-1 to explore the role of YTHDF2 in various cellular processes and potential therapeutic interventions.

    In stock View Details
    5 mg
    $210.00
    10 mg
    $345.00
    All 5 sizes

2 Items

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