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YTHDF

YT521-B homology domain family (YTHDF) proteins participate in recognition of methylated ribonucleic acid (RNA). The family is studied as part of post-transcriptional regulation, linking chemical marks on transcripts to their cellular handling. YTH-IN-1 is listed as an inhibitor across several YTH domain proteins, while YTHDF2 ligand-1 is assigned as a ligand of family member 2. The selection also contains compounds with broader biological annotations. These differences matter when distinguishing direct reader-protein ligands from compounds associated with related pathways.

1 Item

  • YTHDF2 ligand-1
    Cat. No.
    A57868
    CAS No.
    3093182-34-1

    YTHDF2 ligand-1

    YTHDF2 ligand-1 is a selective and high-affinity ligand that targets YTHDF2, with an IC50 of 11 μM and a Kd of 1.3 μM. This compound effectively competes with m6A-RNA for the binding site on YTHDF2, making it a valuable tool for studies involving RNA methylation and its implications in cancer research. Researchers can utilize YTHDF2 ligand-1 to explore the role of YTHDF2 in various cellular processes and potential therapeutic interventions.

    In stock View Details
    5 mg
    $210.00
    10 mg
    $345.00
    All 5 sizes

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