YTHDF

YT521-B homology domain family (YTHDF) proteins participate in recognition of methylated ribonucleic acid (RNA). The family is studied as part of post-transcriptional regulation, linking chemical marks on transcripts to their cellular handling. YTH-IN-1 is listed as an inhibitor across several YTH domain proteins, while YTHDF2 ligand-1 is assigned as a ligand of family member 2. The selection also contains compounds with broader biological annotations. These differences matter when distinguishing direct reader-protein ligands from compounds associated with related pathways.

1 Item

  • YTH-IN-1
    Cat. No.
    A40285

    YTH-IN-1

    YTH-IN-1 is a pan-YTH domain inhibitor that targets various YTH domain-containing proteins. It exhibits IC50 values of 39 μM, 34 μM, 35 μM, 48 μM, and 30 μM for human YTHDF1, YTHDF2, YTHDF3, YTHDC1, and YTHDC2 respectively. This compound is utilized in research to explore the role of YTH domain proteins in RNA metabolism and epitranscriptomics, making it a valuable tool for studying gene regulation and cellular responses.

    1 mg
    $195.00
    5 mg
    $485.00
    All 6 sizes

1 Item

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