(-)-Epipodophyllotoxin is an apoptosis inducer derived from the American mayapple, Podophyllum peltatum. Exhibiting potent antiproliferative activity, it demonstrates GI50 values of 0.36 and 0.24 μM against HeLa and MCF-7 cancer cell lines, respectively. Additionally, (-)-Epipodophyllotoxin has been shown to inhibit mitotic spindle assembly in vitro, making it a valuable reagent for cancer research and studies involving cell cycle dynamics.
(-)-Epipodophyllotoxin is an apoptosis inducer derived from the American mayapple, Podophyllum peltatum. Exhibiting potent antiproliferative activity, it demonstrates GI50 values of 0.36 and 0.24 μM against HeLa and MCF-7 cancer cell lines, respectively. Additionally, (-)-Epipodophyllotoxin has been shown to inhibit mitotic spindle assembly in vitro, making it a valuable reagent for cancer research and studies involving cell cycle dynamics.
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