Fig. 1 · Structure
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Epitheaflagallin 3-O-gallate
MMP Inhibitor
Epitheaflagallin 3-O-gallate is a selective matrix metalloproteinase (MMP) inhibitor. This minor polyphenol, found in black tea, exhibits significant anti-inflammatory and antioxidative properties. It effectively inhibits pancreatic lipase and Streptococcus sorbinus glycosyltransferase, while also reducing the activity and synthesis of MMP-1 and MMP-3 in human gingival fibroblasts. These biological activities make it a valuable tool for research in inflammation and tissue remodeling studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 102067-92-5 |
| Applications | MMP Inhibitor |
| Formula | C27H20O13 |
| Molecular Weight | 552.44 |
| SMILES | O=C(O[C@H]1[C@@H](C(C=C2O)=CC3=CC(O)=C(O)C(O)=C3C2=O)OC4=CC(O)=CC(O)=C4C1)C5=CC(O)=C(O)C(O)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.