Epmedin C

Catalog No.: A12049
Anti-inflammatory Agent
Epmedin C is an orally active anti-inflammatory agent and immunomodulator that targets multiple key proteins, including UCP1, Caspase-1, CDK2, and Keap1. This compound effectively inhibits epithelial cell proliferation by disrupting the CDK2/Cyclin E complex, while also upregulating Nrf2 expression, reducing reactive oxygen species levels, and inhibiting the secretion of pro-inflammatory cytokines. Through these mechanisms, Epmedin C aids in restoring antibody production and alleviating tissue damage, making it relevant for research on conditions such as obesity, immunotoxicity induced by Deoxynivalenol, and mammary hyperplasia.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$45.00
In stock
25mg
$70.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEpmedin C is an orally active anti-inflammatory agent and immunomodulator that targets multiple key proteins, including UCP1, Caspase-1, CDK2, and Keap1. This compound effectively inhibits epithelial cell proliferation by disrupting the CDK2/Cyclin E complex, while also upregulating Nrf2 expression, reducing reactive oxygen species levels, and inhibiting the secretion of pro-inflammatory cytokines. Through these mechanisms, Epmedin C aids in restoring antibody production and alleviating tissue damage, making it relevant for research on conditions such as obesity, immunotoxicity induced by Deoxynivalenol, and mammary hyperplasia.
Product Information
Catalog NumA12049
FormulaC39H50O19
Molecular Weight822.80
CAS Number110642-44-9
SMILESO[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC(O)=C(C(C(O[C@H]3[C@H](O[C@]4([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@H](C)O3)=C(C5=CC=C(OC)C=C5)O6)=O)C6=C2C/C=C(C)/C)[C@@H]1O
SynonymsEpimedin-C; Baohuoside-VI
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