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PRMT6 inhibitor

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Catalog No. A16377

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
EPZ020411 5mg A16377-5
EPZ020411 10mg A16377-10
EPZ020411 50mg A16377-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.


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Chemical Information

Catalog Num A16377
Actions Inhibitor
M. Wt 442.59
Formula C25H38N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1700663-41-7
Synonyms EPZ-020411
SMILES CN(CC1=CNN=C1C2=CC=C(O[[email protected]@H]3C[[email protected]@H](OCCC4CCOCC4)C3)C=C2)CCNC

Biological Activity

EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.59 mL 112.97 mL 225.94mL
0.5 mM 4.52 mL 22.59 mL 45.19 mL
1 mM 2.26 mL 11.3 mL 22.59 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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