xc(-) Cystine/Glutamate Transporter System Inhibitor, ferroptosis inducer
Erastin2 is a selective inhibitor of the xc(-) cystine/glutamate transporter, functioning as a potent inducer of ferroptosis. This compound disrupts intracellular cystine availability, leading to increased oxidative stress and subsequent cell death. Erastin2 is valuable for research applications targeting ferroptosis in cancer biology and neurodegenerative diseases, providing insights into therapeutic strategies that exploit this regulated cell death pathway.
Erastin2 is a selective inhibitor of the xc(-) cystine/glutamate transporter, functioning as a potent inducer of ferroptosis. This compound disrupts intracellular cystine availability, leading to increased oxidative stress and subsequent cell death. Erastin2 is valuable for research applications targeting ferroptosis in cancer biology and neurodegenerative diseases, providing insights into therapeutic strategies that exploit this regulated cell death pathway.
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