Erlotinib-13C6 hydrochloride is a stable isotope-labeled derivative of Erlotinib hydrochloride, targeting the epidermal growth factor receptor (EGFR) kinase with an IC50 of 2 nM. This compound serves as a valuable tool in click chemistry applications due to its alkyne group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its isotopic labeling facilitates quantitative analysis in metabolic studies and drug metabolism research.
Erlotinib-13C6 hydrochloride is a stable isotope-labeled derivative of Erlotinib hydrochloride, targeting the epidermal growth factor receptor (EGFR) kinase with an IC50 of 2 nM. This compound serves as a valuable tool in click chemistry applications due to its alkyne group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its isotopic labeling facilitates quantitative analysis in metabolic studies and drug metabolism research.
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