Estetrol-d4 (Major) is a deuterium-labeled derivative of Estetrol, a selective nuclear estrogen receptor modulator primarily synthesized by the human fetal liver during pregnancy. Estetrol demonstrates affinity for estrogen receptors ERα and ERβ, enhancing eNOS expression and nitric oxide synthesis in endothelial cells. Its estrogenic effects are noted in the endometrium and central nervous system, while exhibiting antagonistic properties in breast tissue. This reagent is valuable in research applications involving contraception and menopausal hormone therapy studies.
Estetrol-d4 (Major) is a deuterium-labeled derivative of Estetrol, a selective nuclear estrogen receptor modulator primarily synthesized by the human fetal liver during pregnancy. Estetrol demonstrates affinity for estrogen receptors ERα and ERβ, enhancing eNOS expression and nitric oxide synthesis in endothelial cells. Its estrogenic effects are noted in the endometrium and central nervous system, while exhibiting antagonistic properties in breast tissue. This reagent is valuable in research applications involving contraception and menopausal hormone therapy studies.
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