Fig. 1 · Structure
Documents & Downloads
Estradiol 17-(β-D-Glucuronide) sodium
Cholestatic Agent
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of estrogen, primarily acting as a cholestatic agent. It functions as a substrate for the organic anion-transporting polypeptide family (Oatp) and the multidrug resistance-associated protein 2 (Mrp2), regulating MRP8-mediated transport processes. This compound induces an immediate and reversible reduction in bile flow and acute intrahepatic cholestasis in female rats while leaving bile acid composition unchanged. It is valuable in research related to the mechanisms of intrahepatic cholestasis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 15087-02-2 |
| Applications | Cholestatic Agent |
| Formula | C24H31NaO8 |
| Molecular Weight | 470.49 |
| SMILES | C[C@@]12[C@](CC[C@@H]2O[C@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O[Na])=O)([H])[C@@]4([H])[C@](C5=C(C=C(O)C=C5)CC4)([H])CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.