ETH-615

Catalog No.: A76410
5-lipoxygenase Inhibitor
ETH-615 is a potent inhibitor of 5-lipoxygenase, an enzyme involved in the biosynthesis of leukotrienes, which play a significant role in inflammatory processes. This compound demonstrates key biological activity in reducing inflammation and may have implications for research into cardiovascular diseases and other inflammatory disorders. Its efficacy in modulating leukotriene synthesis makes ETH-615 valuable for studies aimed at understanding the underlying mechanisms of cardiovascular pathology.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionETH-615 is a potent inhibitor of 5-lipoxygenase, an enzyme involved in the biosynthesis of leukotrienes, which play a significant role in inflammatory processes. This compound demonstrates key biological activity in reducing inflammation and may have implications for research into cardiovascular diseases and other inflammatory disorders. Its efficacy in modulating leukotriene synthesis makes ETH-615 valuable for studies aimed at understanding the underlying mechanisms of cardiovascular pathology.
Product Information
Catalog NumA76410
FormulaC31H25FN2O3
Molecular Weight492.54
CAS Number133430-69-0
SMILESO=C(O)C1=CC=C(CN(CC2=CC=CC(F)=C2)C3=CC=C(OCC4=NC5=CC=CC=C5C=C4)C=C3)C=C1
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