Ethyl 2-(3-hydroxycyclobutyl)acetate

Catalog No.: A84032
PROTAC Linker
Ethyl 2-(3-hydroxycyclobutyl)acetate serves as a PROTAC linker facilitating the development of proteolysis-targeting chimeras. This compound plays a crucial role in the synthesis of innovative PROTACs aimed at selectively degrading specific proteins within cellular systems. Its application is vital for advancing therapeutic strategies in areas such as cancer research and targeted protein degradation studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEthyl 2-(3-hydroxycyclobutyl)acetate serves as a PROTAC linker facilitating the development of proteolysis-targeting chimeras. This compound plays a crucial role in the synthesis of innovative PROTACs aimed at selectively degrading specific proteins within cellular systems. Its application is vital for advancing therapeutic strategies in areas such as cancer research and targeted protein degradation studies.
Product Information
Catalog NumA84032
FormulaC8H14O3
Molecular Weight158.20
CAS Number1408075-22-8
SMILESO=C(OCC)CC1CC(O)C1
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