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Ethyl 2-(3-hydroxycyclobutyl)acetate

PROTAC Linker

Ethyl 2-(3-hydroxycyclobutyl)acetate serves as a PROTAC linker facilitating the development of proteolysis-targeting chimeras. This compound plays a crucial role in the synthesis of innovative PROTACs aimed at selectively degrading specific proteins within cellular systems. Its application is vital for advancing therapeutic strategies in areas such as cancer research and targeted protein degradation studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1408075-22-8
Applications	PROTAC Linker
Formula	C₈H₁₄O₃
Molecular Weight	158.20
SMILES	O=C(OCC)CC1CC(O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.