Fig. 1 · Structure
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
Drug Intermediate
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a versatile drug intermediate that facilitates the synthesis of kinase inhibitors targeting Cdk4, PDGF, FGF, and EGF pathways. This compound exhibits significant potential in medicinal chemistry and pharmaceutical research, contributing to the development of therapies aimed at regulating cell proliferation and differentiation. Its structural versatility makes it a valuable building block for the design of innovative drug candidates.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5909-24-0 |
| Applications | Drug Intermediate |
| Formula | C8H9ClN2O2S |
| Molecular Weight | 232.69 |
| SMILES | O=C(OCC)C1=CN=C(SC)N=C1Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.