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Ethyl 4-oxobutanoate

PROTAC Linker

Ethyl 4-oxobutanoate serves as an effective PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in linking target proteins to E3 ligases, enabling targeted degradation of specific proteins within cellular environments. Its application in drug discovery and development makes it a valuable tool for researchers exploring novel therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	10138-10-0
Applications	PROTAC Linker
Formula	C₆H₁₀O₃
Molecular Weight	130.14
SMILES	O=CCCC(=O)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.