Fig. 1 · Structure
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ETX0282
Cat. No.
A50614
CAS
2209871-83-8
β-lactamase inhibitor
ETX0282 is a β-lactamase inhibitor that functions as an orally active prodrug, converted in the liver to its active form, ETX1317. This compound demonstrates excellent stability during intestinal absorption and enhances the efficacy of antibiotics, like Cefpodoxime Proxetil, in reducing bacterial load in models of neutropenic infections. ETX0282 is useful for research focused on combating infections caused by drug-resistant Gram-negative bacteria.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2209871-83-8 |
| Applications | β-lactamase inhibitor |
| Formula | C13H18FN3O5 |
| Molecular Weight | 315.30 |
| SMILES | O=C(OC(C)C)[C@H](ON1[C@]2([H])C(C)=C[C@@H](C(N)=O)[N@@](C2)C1=O)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.