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Eucalbanin B

5α-reductase Inhibitor

Eucalbanin B, a dimeric tannic acid, functions as a potent inhibitor of 5α-reductase, thereby decreasing dihydrotestosterone (DHT) production. This compound exhibits notable anti-inflammatory properties, effectively diminishing the levels of pro-inflammatory cytokines such as IL-6, IL-8, IL-1β, and TNF-α. Additionally, Eucalbanin B demonstrates strong inhibitory effects on the proliferation of benign prostatic hyperplasia (BPH) cell lines and promotes apoptosis in BPH cells. It is a valuable reagent for research focused on BPH and related inflammatory conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	95263-69-7
Applications	5α-reductase Inhibitor
Formula	C₆₈H₅₀O₄₄
Molecular Weight	1571.10
Synonyms	Cornusiin A
SMILES	OC1=CC(C(OC[C@@H]2[C@H]([C@H](OC(C3=CC(O)=C(O)C(O)=C3)=O)[C@@H](OC(C4=CC(O)=C(O)C(O)=C4OC5=CC(C(OC[C@@H]6[C@@H]7[C@H](OC(C8=CC(O)=C(O)C(O)=C8)=O)[C@H](C(O)O6)OC(C9=CC(O)=C(O)C(O)=C9)=O)=O)=C(C%10=C(O)C(O)=C(O)C=C%10C(O7)=O)C(O)=C5O)=O)C(O)O2)O%11)=O)=C(C%12=C(O)C(O)=C(O)C=C%12C%11=O)C(O)=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.