Euphol is a tetracyclic triterpene alcohol derived from the sap of Euphorbia tirucalli, primarily targeting monoacylglycerol lipase (MGL). This compound exhibits anti-mutagenic, anti-inflammatory, and immunomodulatory properties, making it relevant in pain research and the study of the endocannabinoid system. Euphol reversibly inhibits MGL activity, with an IC50 of 315 nM, thereby modulating inflammatory pain pathways in peripheral tissues.
Euphol is a tetracyclic triterpene alcohol derived from the sap of Euphorbia tirucalli, primarily targeting monoacylglycerol lipase (MGL). This compound exhibits anti-mutagenic, anti-inflammatory, and immunomodulatory properties, making it relevant in pain research and the study of the endocannabinoid system. Euphol reversibly inhibits MGL activity, with an IC50 of 315 nM, thereby modulating inflammatory pain pathways in peripheral tissues.
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