Everolimus-d4

Catalog No.: A31173
Stable Isotope
Everolimus-d4 is a deuterium-labeled derivative of Everolimus, a potent and selective inhibitor of mTOR1. By binding to FKBP-12, Everolimus-d4 forms an immunosuppressive complex that effectively inhibits tumor cell proliferation, while simultaneously inducing apoptosis and autophagy. This stable isotope is valuable for research applications in oncology and immunology, facilitating studies on the therapeutic mechanisms and metabolic pathways associated with mTOR inhibition.
Grouped product items
Size Price Stock Qty
500µg
$290.00
In stock
1mg
$520.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEverolimus-d4 is a deuterium-labeled derivative of Everolimus, a potent and selective inhibitor of mTOR1. By binding to FKBP-12, Everolimus-d4 forms an immunosuppressive complex that effectively inhibits tumor cell proliferation, while simultaneously inducing apoptosis and autophagy. This stable isotope is valuable for research applications in oncology and immunology, facilitating studies on the therapeutic mechanisms and metabolic pathways associated with mTOR inhibition.
Product Information
Catalog NumA31173
FormulaC53H79D4NO14
Molecular Weight962.25
CAS Number1338452-54-2
SMILESO=C1N2[C@](CCCC2)([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C([C@H](C[C@@]3([H])O[C@@](C1=O)([C@@H](CC3)C)O)OC)\C)C)C)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H]4C[C@H]([C@@H](CC4)OC([2H])([2H])C([2H])([2H])O)OC)=O
SynonymsRAD001-d4; SDZ-RAD-d4
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