Fig. 1 · Structure
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Evifacotrep
Cat. No.
A68734
CAS
2413739-88-3
TRPC5 Antagonist
Evifacotrep is a potent antagonist of the transient receptor potential channel 5 (TRPC5) with an IC50 of ≤50 nM. This compound effectively inhibits TRPC5/TRPC4 activity, making it a valuable tool for investigating neurological diseases. Its selective mechanism of action allows for detailed study of TRPC channel involvement in various pathophysiological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2413739-88-3 |
| Applications | TRPC5 Antagonist |
| Formula | C18H12ClF4N5O2 |
| Molecular Weight | 441.77 |
| SMILES | O=C1NN=CC(N2CC3=C(CC2)C(OC4=CC=C(C=C4C(F)(F)F)F)=NC=N3)=C1Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.