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Evifacotrep

Catalog No.: A68734
TRPC5 Antagonist
Evifacotrep is a potent antagonist of the transient receptor potential channel 5 (TRPC5) with an IC50 of ≤50 nM. This compound effectively inhibits TRPC5/TRPC4 activity, making it a valuable tool for investigating neurological diseases. Its selective mechanism of action allows for detailed study of TRPC channel involvement in various pathophysiological processes.
Evifacotrep 2413739-88-3 TRPC5 Antagonist
Grouped product items
Size Price Stock Qty
1mg
$70.00
In stock
5mg
$160.00
In stock
10mg
$265.00
In stock
25mg
$410.00
In stock
50mg
$595.00
In stock
100mg
$865.00
In stock
200mg
$1,270.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEvifacotrep is a potent antagonist of the transient receptor potential channel 5 (TRPC5) with an IC50 of ≤50 nM. This compound effectively inhibits TRPC5/TRPC4 activity, making it a valuable tool for investigating neurological diseases. Its selective mechanism of action allows for detailed study of TRPC channel involvement in various pathophysiological processes.
Product Information
Catalog NumA68734
FormulaC18H12ClF4N5O2
Molecular Weight441.77
CAS Number2413739-88-3
SMILESO=C1NN=CC(N2CC3=C(CC2)C(OC4=CC=C(C=C4C(F)(F)F)F)=NC=N3)=C1Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Membrane Transporters-Ion Channels > TRP Channel