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Exatecan-mpGNNG

Catalog No.: A41473
ADC Linker-payload
Exatecan-mpGNNG is a linker-payload component designed for use in antibody-drug conjugates (ADCs). It integrates Exatecan, a highly effective inhibitor of topoisomerase I, facilitating targeted delivery of therapeutic agents to cancer cells. This compound is particularly relevant for research applications focusing on ADC development and the evaluation of antitumor efficacy.
Exatecan-mpGNNG 3076725-05-5 ADC Linker-payload
Grouped product items
Size Price Stock Qty
5mg
$780.00
In stock
10mg
$1,285.00
In stock
25mg
$2,580.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionExatecan-mpGNNG is a linker-payload component designed for use in antibody-drug conjugates (ADCs). It integrates Exatecan, a highly effective inhibitor of topoisomerase I, facilitating targeted delivery of therapeutic agents to cancer cells. This compound is particularly relevant for research applications focusing on ADC development and the evaluation of antitumor efficacy.
Product Information
Catalog NumA41473
FormulaC43H45FN10O13
Molecular Weight928.88
CAS Number3076725-05-5
SMILESO=C(C=CC1=O)N1CCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker