Ezlopitant is a selective non-peptidic antagonist of the neurokinin-1 (NK-1) receptor. It effectively inhibits both acute and delayed emetic responses induced by cisplatin in animal models by targeting NK-1 receptors in the central nervous system. This compound shows potential for research applications in pain management, chemotherapy-induced nausea and vomiting, and the study of irritable bowel syndrome.
Ezlopitant is a selective non-peptidic antagonist of the neurokinin-1 (NK-1) receptor. It effectively inhibits both acute and delayed emetic responses induced by cisplatin in animal models by targeting NK-1 receptors in the central nervous system. This compound shows potential for research applications in pain management, chemotherapy-induced nausea and vomiting, and the study of irritable bowel syndrome.
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