Fig. 1 · Structure

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Fasitibant chloride hydrochloride

Bradykinin B2 Receptor Antagonist

Fasitibant chloride hydrochloride is a selective and high-affinity antagonist of the bradykinin B2 receptor, exhibiting potent and long-lasting activity. This compound is specifically investigated for its proinflammatory effects and is valuable in research focused on osteoarthritis and rheumatoid arthritis. Its mechanism offers insights into bradykinin-mediated pathways and potential therapeutic interventions in inflammatory conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 869880-33-1
Applications Bradykinin B2 Receptor Antagonist
Formula C36H50Cl4N6O6S
Molecular Weight 836.70
Synonyms MEN16132
SMILES
O=C(N(CC1)CCN1C([C@@H](N)CCC[N+](C)(C)C)=O)C2(CCOCC2)N[S](=O)(C(C=CC(Cl)=C3COC4=CC=CC(C(C)=C5)=C4N=C5C)=C3Cl)=O.[Cl-].Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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