FD 12-9

Catalog No.: A18393

P-gp/BCRP dual inhibitor

FD 12-9

FD 12-9 Chemical Structure

CAS NO. 1451741-22-2

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.39 mL 56.95 mL 113.9 mL
0.5 mM 2.28 mL 11.39 mL 22.78 mL
1 mM 1.14 mL 5.7 mL 11.39 mL
5 mM 0.23 mL 1.14 mL 2.28 mL

*The above data is based on the productmolecular weight 877.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18393
Actions Inhibitor
M. Wt 877.93
Formula C51H47N3O11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1451741-22-2
Synonyms FD-12-9, FD129
SMILES O=C(OC)C1=CC=CC(COC2=C(C3=CC=C(OCCOCCOCCN4N=NC(CCCCOC5=CC=C6C(C=C(C7=CC=CC=C7)OC6=C5)=O)=C4)C=C3)OC8=CC=CC=C8C2=O)=C1

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