Fig. 1 · Structure
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Febuxostat impurity 8
XO Inhibitor
Febuxostat impurity 8 is a structural impurity associated with Febuxostat, a selective inhibitor of xanthine oxidase (XO) with a Ki of 0.6 nM. This compound is valuable for studies examining enzymatic activity and inhibition mechanisms related to purine metabolism. Its utility extends to pharmacokinetic and safety evaluations in research applications focused on gout treatment and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 144060-62-8 |
| Applications | XO Inhibitor |
| Formula | C16H17NO4S |
| Molecular Weight | 319.38 |
| SMILES | O=C(C1=C(C)N=C(C2=CC=C(OCC(C)C)C(C=O)=C2)S1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.