Ferroptosis inducer-13 is a 5′-prenylated chalcone derivative that targets and induces ferroptosis in human non-small cell lung cancer (NSCLC) cells by modulating the Nrf2/xCT/GPX4 pathway. This compound demonstrates significant anti-proliferative effects in vitro and effectively inhibits tumor growth in NSCLC mouse models. Ferroptosis inducer-13 serves as a valuable tool for research focused on the mechanisms and treatment of NSCLC.
Ferroptosis inducer-13 is a 5′-prenylated chalcone derivative that targets and induces ferroptosis in human non-small cell lung cancer (NSCLC) cells by modulating the Nrf2/xCT/GPX4 pathway. This compound demonstrates significant anti-proliferative effects in vitro and effectively inhibits tumor growth in NSCLC mouse models. Ferroptosis inducer-13 serves as a valuable tool for research focused on the mechanisms and treatment of NSCLC.
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