Ferroptosis inducer-4 is a potent ferroptosis inducer that introduces terminal double bonds at the sn-2 position of phospholipids. This compound exhibits significant cytotoxicity in HT-1080 cells, with an IC50 of 18 μM, through the generation of lipid peroxides leading to oxidative damage of the cell membrane. Ferroptosis inducer-4 is valuable for research involving the regulation and mechanisms of ferroptosis in various biological contexts.
Ferroptosis inducer-4 is a potent ferroptosis inducer that introduces terminal double bonds at the sn-2 position of phospholipids. This compound exhibits significant cytotoxicity in HT-1080 cells, with an IC50 of 18 μM, through the generation of lipid peroxides leading to oxidative damage of the cell membrane. Ferroptosis inducer-4 is valuable for research involving the regulation and mechanisms of ferroptosis in various biological contexts.
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