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FF-C1

CerS6 Inhibitor, Ceramide Synthesis Inhibitor, Acetylcholinesterase Inhibitor

FF-C1 is a non-competitive inhibitor of Ceramide Synthase 6 (CerS6), exhibiting an IC50 of 7.89 μM. By inhibiting intestinal CerS6, FF-C1 effectively lowers serum ceramide levels, offering protective effects against metabolic dysfunction-associated steatohepatitis. This compound is also reported to inhibit acetylcholinesterase, highlighting its potential applications in studying metabolic disorders and neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1665292-06-7
Applications	CerS6 Inhibitor, Ceramide Synthesis Inhibitor, Acetylcholinesterase Inhibitor
Formula	C₁₅H₁₄O₅
Molecular Weight	274.27
SMILES	O=C1C2=C(C(C=C1OC)=O)C(O)=C(C)C3=C2O[C@@H](C)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.