FFN 206 dihydrochloride is a selective substrate for the Vesicular Monoamine Transporter 2 (VMAT2), exhibiting an apparent Km of 1.16 μM. This fluorescent probe enables the detection of VMAT2 activity in intact cells via fluorescence microscopy, allowing for the visualization of subcellular localization to VMAT2-expressing acidic compartments while minimizing labeling of other organelles. Its application is essential for studying monoamine transport dynamics and cellular compartmentalization in neurobiological research.
FFN 206 dihydrochloride is a selective substrate for the Vesicular Monoamine Transporter 2 (VMAT2), exhibiting an apparent Km of 1.16 μM. This fluorescent probe enables the detection of VMAT2 activity in intact cells via fluorescence microscopy, allowing for the visualization of subcellular localization to VMAT2-expressing acidic compartments while minimizing labeling of other organelles. Its application is essential for studying monoamine transport dynamics and cellular compartmentalization in neurobiological research.
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