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$0.00 - Chen CC, .et al. The Genomic Alterations of 5α-Reductases and Their Inhibitor Finasteride-s Effect in Bladder Cancer, Anticancer Res, 2017, Dec;37(12):6893-6898 PMID: 29187470
Biological Activity
Finasteride is a synthetic type II 5α-reductase inhibitor. This enzyme converts testosterone to dihydrotestosterone (DHT).
Targets
| 5-α reductase | ||||
| 10.2 nM(Ki) |
| In vitro | DMSO | 75 mg/mL (201.32 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 75 mg/mL (201.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.85 mL | 134.23 mL | 268.46 mL |
| 0.5 mM | 5.37 mL | 26.85 mL | 53.69 mL |
| 1 mM | 2.68 mL | 13.42 mL | 26.85 mL |
| 5 mM | 0.54 mL | 2.68 mL | 5.37 mL |
*The above data is based on the productmolecular weight 372.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10387 |
|---|---|
| M. Wt | 372.5 |
| Formula | C23H36N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 98319-26-7 |
| Synonyms | Proscar, Propecia |
| SMILES | C[[email protected]]12CC[[email protected]]3[[email protected]]([[email protected]@H]1CC[[email protected]@H]2C(=O)NC(C)(C)C)CC[[email protected]@H]4[[email protected]@]3(C=CC(=O)N4)C |
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