Fig. 1 · Structure
Documents & Downloads
Firefly luciferase-IN-5
Luciferase Inhibitor
Firefly luciferase-IN-5 is a potent inhibitor of ATP-dependent luciferase, specifically targeting Firefly luciferase. It demonstrates nanomolar-level inhibitory activity against various luciferase variants, including GRLuc (pIC50 = 8.5), RLuc8 (pIC50 = 7.5), and RLuc (pIC50 = 5.5). This inhibitor is valuable for research applications involving luciferase-based assays, enabling precise modulation of bioluminescent signaling and facilitating studies in gene expression, signal transduction, and molecular imaging.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 959557-37-0 |
| Applications | Luciferase Inhibitor |
| Formula | C23H24N4O3S |
| Molecular Weight | 436.53 |
| SMILES | O=S(NCC1=NC2=C(N1CC3=CC=C(C=C3)OC)N=CC=C2)(C4=CC=C(C)C(C)=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.