Fig. 1 · Structure
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FK-788
IP Agonists
FK-788 is a potent PGI(2) and IP receptor agonist, exhibiting significant anti-aggregation activity with an IC50 of 18 nM. It demonstrates a high binding affinity for the human recombinant IP receptor, characterized by a Ki value of 20 nM. This compound is valuable for research applications focused on studying platelet aggregation and vascular function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 227951-89-5 |
| Applications | IP Agonists |
| Formula | C26H25NO6 |
| Molecular Weight | 447.48 |
| SMILES | O=C(O)COC1=C2CC[C@](O)(COC(N(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC2=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.