Fig. 1 · Structure

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FL-166

Mpro Inhibitor

FL-166 is a potent inhibitor of the SARS coronavirus main protease (Mpro) with a Ki value of 40 nM. This compound functions by targeting a specific cluster of serine residues in proximity to the protease's active site, thereby effectively disrupting its enzymatic activity. FL-166 is valuable for research applications focused on studying SARS-CoV and investigating potential therapeutic strategies against coronavirus infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 693235-40-4
Applications Mpro Inhibitor
Formula C20H16B2N4O10
Molecular Weight 493.98
SMILES
O=C(C1=CC(B(O)O)=CC([N+]([O-])=O)=C1)NC2=CC=C(NC(C3=CC(B(O)O)=CC([N+]([O-])=O)=C3)=O)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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