FL118, a potent survivin inhibitor, is a synthetic analogue of camptothecin (10,11-(Methylenedioxy)-20(S)-camptothecin). It functions by binding to the oncoprotein DDX5 (p68), leading to its dephosphorylation and degradation. FL118 is instrumental for cancer research, providing valuable insights into therapeutic strategies targeting survivin-related pathways.
FL118, a potent survivin inhibitor, is a synthetic analogue of camptothecin (10,11-(Methylenedioxy)-20(S)-camptothecin). It functions by binding to the oncoprotein DDX5 (p68), leading to its dephosphorylation and degradation. FL118 is instrumental for cancer research, providing valuable insights into therapeutic strategies targeting survivin-related pathways.
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