Flaccidoside II

Catalog No.: A33063
Apoptosis Inducer
Flaccidoside II is a potent apoptosis inducer that targets malignant peripheral nerve sheath tumors (MPNSTs). This active triterpenoid saponin, derived from the rhizome of Anemone flaccida, effectively inhibits proliferation and triggers apoptotic pathways in cancer cell lines. Additionally, Flaccidoside II demonstrates therapeutic potential in mitigating collagen-induced arthritis in murine models, making it a valuable reagent for research in cancer and inflammatory diseases.
Grouped product items
Size Price Stock Qty
1mg
$375.00
In stock
5mg
$960.00
In stock
10mg
$1,575.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFlaccidoside II is a potent apoptosis inducer that targets malignant peripheral nerve sheath tumors (MPNSTs). This active triterpenoid saponin, derived from the rhizome of Anemone flaccida, effectively inhibits proliferation and triggers apoptotic pathways in cancer cell lines. Additionally, Flaccidoside II demonstrates therapeutic potential in mitigating collagen-induced arthritis in murine models, making it a valuable reagent for research in cancer and inflammatory diseases.
Product Information
Catalog NumA33063
FormulaC59H96O25
Molecular Weight1205.38
CAS Number140694-19-5
SMILESO=C([C@](CC[C@]12C)(CCC3(C)C)[C@](C3)([H])C1=CC[C@@]4([H])[C@]2(CC[C@](C(C)5C)([H])[C@@]4(CC[C@@H]5O[C@H](OC[C@H]6O)[C@@H]([C@H]6O)O[C@H](O[C@H]7C)[C@@H]([C@@H]([C@H]7O)O)O)C)C)O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]([C@H]8O)CO[C@@H]([C@@H]([C@H]9O)O)O[C@@H]([C@H]9O[C@H](O[C@H]%10C)[C@@H]([C@@H]([C@H]%10O)O)O)CO
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