Fig. 1 · Structure

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FLT3 Ligand-Linker Conjugate 1

Target Protein Ligand-Linker Conjugates

FLT3 Ligand-Linker Conjugate 1 functions as a protein ligand-linker conjugate that combines the FLT3 ligand with a PROTAC linker, enabling the recruitment of the E3 ligase VHL. This conjugate is instrumental in the synthesis of PROTAC RSS0680, a bifunctional compound that facilitates the targeted degradation of kinases. It serves as a valuable tool in research applications aimed at understanding the role of FLT3 in various biological processes and therapeutic contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2769753-49-1
Applications Target Protein Ligand-Linker Conjugates
Formula C29H34N6O4S2
Molecular Weight 594.75
SMILES
CS(NC1=CC=CC(C2=CSC3=CN=C(N=C23)NC4=CC=C(N5CCN(CC5)CCCCCC(O)=O)C=C4)=C1)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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