Documents & Downloads

FMK 9a

Name: FMK 9a
Brand: Adooq Bioscience
SKU: A12603
Availability: InStock

Cat. No. A12603 CAS 1955550-51-2

autophagin-1 inhibitor

FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Biological Activity

Cellular Effect

Cell Line	Activity	Value	Description	Reference
CHO	IC50	> 100 μM	Inhibition of recombinant human cathepsin D (400 residues) expressed in CHO cells using 5-FAM/QXL 520 FRET peptide as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis	[PMID: 27563406]
CHO	IC50	0.2 μM	Inhibition of recombinant human cathepsin B (332 residues) expressed in CHO cells using Z-FR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis	[PMID: 27563406]
HEK-293T	CC50	> 100 μM	Cytotoxicity against HEK293T cells after 24 hrs	[PMID: 27563406]

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1955550-51-2
Applications	autophagin-1 inhibitor
Formula	C₂₃H₂₁FN₂O₃
Molecular Weight	392.42
SMILES	O=C(C1=C(C=CC=C2)C2=CC=C1)N[C@H](C(NCC(CF)=O)=O)CC3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Documents & Downloads

FMK 9a

Select a Size

Package Sizes

DMSO Solution

FMK 9a 1 mg